Around 400 kg of hashish has been seized in Afghanistan's southern province of Helmand by the interior ministry, police said.
Smugglers made an armed resistance during the operation. As a result of a gun-battle, one drug dealer was injured and taken to hospital while another was arrested.
Police said the drug dealers intended to transfer the hashish to Pakistan.
Police also arrested a few farmers in the province who owned fields of opium poppies.
Afghanistan is the global production centre for opium and opiates like heroin and hashish.
There has been a significant rise in drug production since the US-led coalition toppled the Taliban in 2001.