Prasad said the party had taken notice of the reports in the media about Sinha's remarks.
"He is a very senior leader of the party. He has given a public statement today. Being a senior leader, all party forums were available to him. Instead, he chose to go public. The party did not deem it appropriate. We urge him to reconsider his remarks," Prasad said.
Sinha told a news agency Tuesday that the issue was not whether Gadkari was guilty but that all party leaders should be above reproach.
Sinha is not the first BJP leader to demand Gadkari's removal.
Senior lawyer and BJP leader Ram Jethmalani too had made a similar demand last month.
His son, Mahesh resigned from BJP's national executive after corruption allegations surfaced against the BJP president.
Gadkari is facing probe over financial dealings of investor companies in a firm linked to him.
The BJP has virtually given Gadkari a clean chit following probe by a financial analyst S. Gurumurthy, considered close to the Rashtriya Swayamsevak Sangh.